CANNABINODIVARIN (CBVD)

What is Cannabinodivarin (CBVD)?

Cannabinol (CBN) though not as prominent as its counterparts such as Cannabidiol (CBD) and tetrahydrocannabinol (THC), is still one of the well-known Cannabinoids that can be found in the Cannabis plant. It is from it that cannabinodivarin is derived. The oxidization of THC Cannabinoid produces Cannabinolis and the process is called degradation process. Cannabinodivarin (CBVD) as one of the compounds of cannabinol, is present in the cannabis plant although very little can be said of it as a result of lack of sufficient studies on it unlike other Cannabinoids. However, no matter how little that can be said, inferences can still be picked from its mother compound; Cannabinol. Thus, cannabinodivarin can be said to be capable of reflecting all the properties as the same as Cannabinol (CBN). The fact that Cannabinol is a non-psychoactive compound increases the tendency of Cannabinodivarin (CBVD) not to be a psychoactive compound too.

CBN was the first phytocannabinoid ever to be isolated from a red oil cannabis extract by Thomas Barlow Wood,  WT Newton Spivey, and Thomas Hill Easterfield in 1896. It wasn’t until 1932 that R.S. Cahn further clarified CBN’s chemical structure, paving the way for the cannabinoid’s chemical synthesis and official discovery by two separate research groups Lord Todd in the UK and Roger Adams in the U.S. in 1940 (Weinberg Bill, 2018; Cadena Aaron, 2019). After its 1940 discovery, the CBN cannabinoid was thought to be the primary psychoactive component of cannabis for more than two decades. Then, Israeli researchers Yechiel Gaoni and Raphael Mechoulam successfully isolated THC in 1964 and discovered its psychoactive dominance within the cannabis plant. This discovery led to further research that identified CBN as an oxidized, degraded version of THC, but without THC’s intoxicating effects.

HOW DOES CBVD WORK?

Much information cannot be accessed to know how it works but since cannabinodivarin (CBVD) is derived from Cannabinol, then it has very high tendency to exhibit the same properties. One of the most valuable aspects of cannabis is the way its cannabinoids offer multiple mechanisms of action, or pathways through which they produce an effect. CBD and THC produce beneficial effects, in part, because they can activate multiple biological pathways at once. CBN is popularly believed to be sedating in effect, The CBN cannabinoid hasn’t been researched nearly as rigorously as CBD, THC, or even some terpenes. It may interact with other cannabinoids and cannabis compounds to enhance a product’s overall therapeutic effect profile, a phenomenon known as the entourage effect (Alex Collins, 2019).

POSSIBLE THERAPEUTIC BENEFITS

Due to the topic debate on the legalization of Cannabis little or no research has been conducted on Cannabinodivarin (CBVD) to ascertain its chemical and pharmacological properties. Nonetheless, since the compound belongs to the category of Cannabinol (CBN), there are probabilities that the two will exhibit similar properties. Hence, Cannabinodivarin can be said to also have therapeutic benefits like Cannabinol (CBN). Cannabinol or CBN offers a unique profile of effects and benefits that makes researcher more interested in its scientific investigation (Alex Collins, 2019). So far, CBN’s studied benefits include:

  • Pain relief
  • Antibacterial
  • Anti-inflammatory
  • Appetite stimulant
  • Regeneration of bone
  • Sedative properties

 

INTERESTING FACTS

Cannabinol (CBN) is known to be one of the most powerful elemets to induce sleep making cannabinodivarin (CBVD) a potential tool for the treatment of sleep related issues such as insomnia, sleep apnea, and other similar sleep disorders.

REFERENCES

Alex Collins. What is CBN and what are the benefits of this cannabinoid? (2019) Accessed 12/09/2020 via: 

Weinberg, Bill (Fall 2018). “U.S. Chemist Roger Adams Isolated CBD 75 Years Ago”. Freedom Leaf (34 ed.). Freedom Leaf. Retrieved 2020-09-12 – via Issuu.com.

Cadena, Aaron (2019-03-08). “The History Of CBD – A Brief Overview”. CBD Origin. CBD Origin.com. Retrieved 2020-09-12.

Mechoulam, Raphael. “Raphael Mechoulam Ph.D.” cannabinoids.huji.ac.il (Biography). The Hebrew University of Jerusalem. Retrieved 2020-09-12

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