CANNABIDIORCOL (CBN-C1)

WHAT IS CANNABIORCOL (CBN-C1)?

Cannabidiorcol (CBN-C1) is one of the several compounds present in Cannabinol (CBN) family. It is a member of Cannabinol (CBN) and Cannabinodiol (CBDL) family having a good number of medical benefits. From the available volume of research, it is evident that little or nothing has been said of Cannabiorcool (CBN-C1). However, inferences can be obtained from the family it belongs to as touching its properties and benefits.

Whether Cannabiorcool (CBN-C1) is a psychoactive or a non-psychoactive compound is still a bone of contention in the medical field today as some holds that the compound has no intoxicating properties while some others argue that the compound has an element of psychotropic ability. Either ways, what is important is to note that, to get a larger percentage of concentration of this compound, the aged Cannabis plant is the best option.

CBND-type cannabinoids are the fully aromatized derivatives of CBD. The first mention of these compounds appeared in 1972. Van Ginneken et al. named a compound isolated from hashish and identified by GC-MS cannabinodiol. This assignment, however, was proven incorrect after the total synthesis of cannabino-diol (CBND-C5). The compound isolated by Van Ginneken et al. was determined to be cannabifuran (CBF-C5) and it was shown that the product from the photochemical conversion of cannabinolis cannabinodiol.

HOW DOES CBNC1 WORK?

Cannabinols (CBN) generally relate with CB1 and CB2 receptors although sharing a greater likeness for CB receptors that the body’s natural endocannabinoid receptor system can produce. Rather than bind to the receptors like Tetrahydrocannabinol (THC), Cannabinols (CBN) act as an agent of physiological change in the human cell that is, it play the role of an agonist to the high-threshold thermo-sensors (TRPV2) to aid medicinal activity. These naturally producing proteins regulate several biological systems in the human body. CBN has been shown to contain antibacterial, analgesic as well as anti-inflammatory properties, but most notably, potently sedative properties.

POSSIBLE THERAPEUTIC BENEFITS?

Obviously, much has not been said of Cannabidiorcol, an assumption can, however be made that the compound exhibits similar properties with slightly different chemical properties to Cannabinols (CBNs) and Cannabinodiols (CBDLs) and although research is low too on that class of Cannabinoids, they however, show traits of being a curative agent for mental diseases especially Alzheimer’s disease alongside other neuro-protective issues.

INTERESTING FACTS

Being part of the CBN and CBDL family, it can function as a pharmacological agent to reduce intra-ocular pressure.

REFERENCES

Appendino, G, et al. “Antibacterial Cannabinoids from Cannabis Sativa: a Structure-Activity Study.” Current Neurology and Neuroscience Reports., U.S. National Library of Medicine, Aug. 2008, 

Vree, T.B., Breimer, D.D., Van Ginneken, C.A.M., Van Rossum, J.M., 1972b. Gas chromatography of cannabis constituents and their synthetic derivatives. Journal of Chromatography 74 (2), 209–224.

Lousberg, R.J.J.C., Bercht, C.A.L., Van Ooyen, R., Spronck, H.J.W., 1977. Cannabinodiol: conclusive identification and synthesis of a new cannabinoid from Cannabis sativa. Phytochemistry 16 (5), 595–597.

Vree, T.B., Breimer, D.D., Van Ginneken, C.A.M., Van Rossum, J.M., 1972b. Gas chromatography of cannabis constituents and their synthetic derivatives. Journal of Chromatography 74 (2), 209–224

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